Big Leagues, today.
Jace, Vryn's Prodigy is headed to $100 near-term on steep sinusoidal ascent, and holding that price for a while. I think that Jace, Vryn's Prodigy will really stick in all formats, for several years, potentially spiking to $150 or more sometime this year. Rotating out of Standard means nothing to this card, in fact the signification that these are definitely out-of-print may have the opposite effect that rotation normally has.
It will certainly be reprinted, but the question is when, and how. It's likely that a FTV reprinting (like Sculptor suffered) will take place at least 18 months from now, plenty of time to grow. Wizards could decide that the next core-esque set needs Jace at Mythic. In that case, we're screwed and price flattens to $30. I think it's a longshot, though. Wizards wants some more meat on Jace, Vryn's Prodigy's bones before it harvests it again. Lots of bread for us, too, then.
The long-term risk is being outmoded by power-creep, i.e future incarnations of Jace that might crowd out 'lil Jace the same way he is crowding out Jace, the Mind Sculptor.
So let's talk about him: Jace, the Mind Sculptor, once the crown jewel of Modern gems. Only one Jace at time, boys and girls, so if Vryn's Prodigy maintains its momentum, it may supplant the Mind Sculptor, financially. Eternal players will start to prefer Vryn's Prodigy, and the two are semi-exclusive . The deflation of Mind Sculptor inflates Vryn's Prodigy, and there's a lot of hot air where that came from...
There is BIG money to made in these. The multiplier effect on demand from speculators and investors will be just enormous once everyone notices the price's upswing into "really serious" financial territory for an in-print card. There is only one precedent, and it's Jace, and look how that went.
FOILS could easily be $400 in a year or two, if Jace follows in... Jace's footsteps. They are a mere $100 now.